Depression makes a person hollow inside. Keep thinking about every little thing, sometimes in sorrow, frustration and sometimes in despair. At the same time, many types of depression make a person very happy and sometimes completely disappointed. But by taking anti-depressant, the reversal of hormones within it brings changes within them. After years of research around the world, anti-depressant medicines were discovered which cure depression patients.
But even the side effects of every medicine do not turn away. Similarly, in the research done so far about the side effects of anti-depressants, it has been revealed that people taking anti-depressant medicines for a long time become completely cool. They are not affected by any negative or positive emotion. They become completely indifferent in the matter of feelings. Recently, in new research, the reason has been found that why this side effect appears after taking anti-depressants.
Professor Barbara Sahakian of the Department of Psychology, University of Cambridge, says that people taking anti-depressants tell about not feeling much. On the other hand, depression itself often reduces the patient’s interest in those activities in which he used to get pleasure earlier. Explain that Prof Sahakian and colleagues have investigated the emotion-reducing effect of SSRI use in people without mental health conditions.
She says that most selective serotonin reuptake inhibitors (SSRIs) are used as antidepressants. They are believed to work by increasing the levels of the chemical serotonin in the brain, although why this improves our mood is not clear. But what is certain is that more than half of people taking antidepressants experience an unwanted reduction in both positive and negative emotions.
This is how research happened
Researchers gave escitalopram or a placebo to 66 people without depression. After three weeks, the participants performed a series of tasks related to memory and learning. Participants who took an antidepressant were 23 percent less sensitive to activation than those who took a placebo. Other tests showed that the drug did not impair their cognitive abilities in other ways. You can read about this research here.
Prof Sahakian says that this research suggests that the side effects of SSRIs reduce people’s sensitivity to rewards or other pleasurable experiences. Another good aspect of this is that these medicines also reduce the intensity of negative emotions, which are helpful in depression.
She further says that I hope that this research will not make doctors more cautious about prescribing antidepressants as they are very necessary medicines. My hope is that this will help doctors discuss potential side effects with patients.
Positive effects of antidepressants are more important than side effects
Katherine Harmer from the University of Oxford tells newscientist.com about the research: “While I don’t think this research should alert doctors to why antidepressants cause emotional blunting in a subset of people, it’s actually an important one.” The question is. I don’t think this result explains why people have this effect, but it could be a marker of it, which could be useful when it comes to developing new treatments that don’t have these side effects . Harmer says the study would have been more useful if participants had also been asked whether they experienced emotions while taking antidepressants because they are such important medications.
Indian psychiatrist Dr. Anil Shekhawat says that anti-depressants are very important medicines, their good effects are more than their side effects. It is more important for the person taking anti-depressant to keep taking it regularly on the advice of the doctor.